Which test will reproduce or intensify symptoms in a patient with sensory loss in the little finger and functional loss in the thumb adduction?

The test that reproduces or intensifies symptoms in a patient experiencing sensory loss in the little finger and functional loss in thumb adduction is direct pressure over the pisohamate. This area is associated with the ulnar nerve, which supplies sensation to the little finger and contributes to intrinsic muscle function in the hand, including the adductor muscle for the thumb.

When direct pressure is applied over the pisohamate, it can exacerbate symptoms related to ulnar nerve compression or irritation, leading to an increase in sensory loss in the little finger and impacting thumb adduction. This makes it a valuable test for identifying issues related to the ulnar nerve in clinical assessments.

The other choices do not specifically address the symptoms of sensory loss in the little finger and functional loss in thumb adduction related to the ulnar nerve's involvement. Wrist flexion could potentially irritate the median or ulnar nerves but doesn’t specifically focus on the symptoms mentioned. Palpation of the median nerve primarily assesses median nerve integrity, which is not directly related to little finger sensory loss. Lastly, active range of motion of the thumb focuses on joint movement and might not effectively reproduce the specific symptoms of nerve involvement in this case.