What stimulates the production of testosterone in Leydig cells?

Luteinizing Hormone (LH) is the hormone that stimulates the production of testosterone in Leydig cells, which are located in the testes. When LH is secreted by the anterior pituitary gland, it binds to specific receptors on Leydig cells, prompting them to convert cholesterol into testosterone through a series of biochemical processes. This stimulation is crucial for the regulation of male reproductive functions, including spermatogenesis and the development of secondary sexual characteristics.

The function of LH in testosterone production is a key component of the hypothalamic-pituitary-gonadal (HPG) axis. This axis regulates various reproductive hormones and emphasizes the importance of LH in maintaining male hormone levels. Understanding this relationship is vital for those studying reproductive endocrinology or preparing for examinations related to these topics.