In which part of the body are Pacinian corpuscles primarily located?

Pacinian corpuscles, also known as lamellar corpuscles, are specialized mechanoreceptors primarily located in the skin, particularly in the deeper layers such as the dermis and subcutaneous tissue. They are responsible for detecting deep pressure and vibration sensations. These structures are adapted to respond to changes in pressure; when activated, they signal the presence of mechanical stimuli to the nervous system.

The skin is the correct answer because it serves as the primary site for the sensory functions that Pacinian corpuscles provide. They are prominent in areas of the body where sensitivity to vibration and pressure is crucial, such as the palms of the hands and soles of the feet. Understanding this localization helps explain how the body perceives different tactile sensations, which is vital for interaction with the environment and the detection of potentially harmful stimuli.